Which assessment finding would concern the nurse if found in the ...

[Caiter2013]

Which assessment finding would concern the nurse if found in the client receiving darunavir (Prezista)?
 
  1. Nausea and vomiting
  2. Constipation
  3. Abdominal pain, headache, and rash
  4. Complete numbness and tingling around the mouth

Question 2

A client who is pregnant is taking ritonavir. When asking about the safety of this medication in pregnancy, the nurse informs the client that this drug is in pregnancy category:
 
  1. X.
  2. B.
  3. C.
  4. A.

[Chou]

Answer to Question 1

Correct Answer: 3
Rationale 1: All antiretrovirals have the potential to cause nausea and vomiting.
Rationale 2: Constipation is not a side effect of the medication.
Rationale 3: Darunavir is a protease inhibitor. The nurse would report signs of fever, abdominal pain, headache, and rash.
Rationale 4: Numbness around the mouth might be reported in NRTIs but it not associated with darunavir.
Global Rationale: Severe rashes are possible, and these call for discontinuation of therapy. Nausea and vomiting are expected adverse effects; constipation and numbness around the mouth are not associated with this drug.

Answer to Question 2

Correct Answer: 2
Rationale 1: Ritonavir is not in pregnancy category X, which is not safe during pregnancy.
Rationale 2: Ritonavir is in pregnancy category B and so is safe during pregnancy.
Rationale 3: Ritonavir is not in pregnancy category C, which is not safe during pregnancy.
Rationale 4: Ritonavir is not in pregnancy category A.
Global Rationale: Ritonavir is in pregnancy category B and is safe during pregnancy. It may be combined with other drugs of other categories and safety in pregnancy should be determined by the categories of all drugs combined.