Answer to Question 1
Correct Answer: 3
Rationale 1: HIV has a rapid replication rate, and a high error or mutation rate, which creates huge numbers of genetic variants. This causes the vaccine to have to try to hit a moving target that is changing genetic makeup every minute.
Rationale 2: HIV has a rapid replication rate.
Rationale 3: HIV has a rapid replication rate.
Rationale 4: HIV has a high error or mutation rate, which creates huge numbers of genetic variants.
Global Rationale: HIV has an extremely rapid replication rate, combined with a high error or mutation rate.
Answer to Question 2
Correct Answer: 1,2
Rationale 1: Many new medications have been discovered due to the research for an HIV vaccination.
Rationale 2: Research for a vaccination for HIV has lead to advances in the treatment and control of HIV.
Rationale 3: Research for a vaccine has not led to new ways to prevent the transmission of HIV.
Rationale 4: Research for an HIV vaccine has not lead to ethical treatment regimens. One problem with the development of an HIV vaccine is how to ethically test the vaccine.
Rationale 5: Vaccine cocktails are not a benefit of the research for an HIV vaccine.
Global Rationale: Vaccine research has not been a total failure. Scientists have learned an enormous amount about the immune system's response to HIV infection. This has promoted the development of new drugs and advanced our understanding of how to treat and control the infection. This research has not led to new ways to prevent transmission, more ethical treatment regimens, or the development of vaccine cocktails.