Answer to Question 1
Correct Answer: 1,2,3,4
Rationale 1: The past few decades have seen a dramatic rise in the incidence of fungal infections due to AIDS. Fungi are much more complex than bacteria and require a different approach to pharmacotherapy.
Rationale 2: The past few decades have seen a dramatic rise in the incidence of fungal infections due to aggressive cancer chemotherapy. Fungi are much more complex than bacteria and require a different approach to pharmacotherapy.
Rationale 3: The past few decades have seen a dramatic rise in the incidence of fungal infections due to the widespread use of indwelling intravenous (IV) catheters. Fungi are much more complex than bacteria and require a different approach to pharmacotherapy.
Rationale 4: The past few decades have seen a dramatic rise in the incidence of fungal infections due to the overuse of broad-spectrum antibiotics. Fungi are much more complex than bacteria and require a different approach to pharmacotherapy.
Rationale 5: There is no evidence that the overuse of antiviral medications has increased the incidence of fungal infections.
Global Rationale: The past few decades have seen a dramatic rise in the incidence of fungal infections due to AIDS, aggressive cancer chemotherapy, the widespread use of indwelling intravenous (IV) catheters, and the use of broad-spectrum antibiotics. There is no evidence that the overuse of antiviral medications has increased the incidence of fungal infections.
Answer to Question 2
Correct Answer: 2
Rationale 1: Continuous medication administration is required, and there is no need for drug holidays.
Rationale 2: Treatment requires many months to fully eradicate the organism.
Rationale 3: Some fungal infections occur in superficial skin layers.
Rationale 4: Fungal infections do not destroy medications.
Global Rationale: Pharmacotherapy of systemic mycoses is often continued for many months to ensure the fungus is eliminated. Continuous medication administration is required, and there is no need for drug holidays. Some fungal infections occur in superficial skin layers. Fungal infections do not destroy medications.