Answer to Question 1
Correct Answer: 2
Rationale 1: Trimethoprim-sulfamethoxazole is a fixed-dose combination sulfonamide, and is the traditional choice for AUC in most communities.
Rationale 2: Metronidazole is a miscellaneous antibacterial that is used to treat protozoal infections, and is often used in the treatment of pelvic infections.
Rationale 3: Norfloxacin is a fluoroquinolone. Fluoroquinolones have become the drug of choice in many communities.
Rationale 4: Fosfomycin blocks cell wall synthesis. Its only indication for use is UTI.
Global Rationale: Metronidazole is a miscellaneous antibacterial that is used to treat protozoal infections, and is often used in the treatment of pelvic infections. Trimethoprim-sulfamethoxazole is a fixed-dose combination sulfonamide, and is the traditional choice for AUC in most communities. Norfloxacin is a fluoroquinolone. Fluoroquinolones have become the drug of choice in many communities. Fosfomycin blocks cell wall synthesis. Its only indication for use is UTI.
Answer to Question 2
Correct Answer: 3
Rationale 1: Nitrofurantoin is a urinary antiseptic taken for a number of days. The client's problem relates to compliance; therefore, the client needs a medication that can be given in one dose.
Rationale 2: Treatment with trimethoprim-sulfamethoxazole requires a number of days, so it is not appropriate for a client with compliance issues.
Rationale 3: Fosfomycin would be the drug of choice for this client because it is given as a single dose, so compliance is not an issue.
Rationale 4: Ciprofloxacin (Cipro) is effective as a three-day regimen, but with the client's problem with compliance, a medication that can be given in one dose would be a better choice.
Global Rationale: Fosfomycin would be the drug of choice for this client because it is given as a single dose, so compliance is not an issue. The other drugs are taken for a number of days and depend upon the client's compliance.
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