Answer to Question 1
Correct Answer: 1
Rationale 1: Platelets are derived from megakaryocytes. Their production is driven by thrombopoietin.
Rationale 2: Colony-stimulating factors do not affect platelet production.
Rationale 3: Interferons do not affect platelet production.
Rationale 4: Erythropoietin does not affect platelet production.
Global Rationale: Platelets are derived from megakaryocytes. Their production is driven by thrombopoietin. Colony-stimulating factors do not affect platelet production. Interferons do not affect platelet production. Erythropoietin does not affect platelet production.
Answer to Question 2
Correct Answer: 2
Rationale 1: Dietary intake of iron supports the construction of the core of the hemoglobin molecule. Amino acids are needed to form the erythropoietin molecule, but dietary intake in itself does not have major effects on the increase in the hormone level.
Rationale 2: The bone marrow is stimulated by erythropoietin from the kidney.
Rationale 3: Bone marrow responds to the stimulus of erythropoietin; it does not produce erythropoietin.
Rationale 4: Iron is needed to make red blood cells, but its absorption is not driven by erythropoietin.
Global Rationale: The bone marrow is stimulated by erythropoietin from the kidney. Dietary intake of iron supports the construction of the core of the hemoglobin molecule. Amino acids are needed to form the erythropoietin molecule, but dietary intake in itself does not have major effects on the increase in the hormone level. Bone marrow responds to the stimulus of erythropoietin; it does not produce erythropoietin. Iron is needed to make red blood cells, but its absorption is not driven by erythropoietin.