Angiotensin-converting enzyme (ACE) inhibitor drugs prevent ACE ...

[c0205847]

Angiotensin-converting enzyme (ACE) inhibitor drugs prevent ACE from breaking down which substances, resulting in some of the serious adverse effects of the ACE inhibitors?
 
  1. Aldosterone
  2. Bradykinin
  3. Renin
  4. RAAS

Question 2

The secretion, storage, and synthesizing of renin are controlled in which cells of the kidney?
 
  1. The distal loop
  2. The baroreceptors
  3. Henle's loop
  4. The juxtaglomerular cells

[blazinlyss]

Answer to Question 1

Correct Answer: 2
Rationale 1: ACE does not break down aldosterone.
Rationale 2: ACE, with several other enzymes, breaks down bradykinin, and if this accumulates, it can cause cough and angioedema.
Rationale 3: ACE does not break down renin.
Rationale 4: ACE is part of the RAAS system; it does not break it down.
Global Rationale: ACE, with several other enzymes, breaks down bradykinin, and if this accumulates, it can cause cough and angioedema. ACE does not break down aldosterone or renin. ACE is part of the RAAS system; it does not break it down.

Answer to Question 2

Correct Answer: 4
Rationale 1: The distal loop is a section of the kidneys, not a group of cells.
Rationale 2: The baroreceptors are located in the heart, not the kidneys.
Rationale 3: Henle's loop is a section of the kidneys, not a group of cells.
Rationale 4: The juxtaglomerular cells (JG) are responsible for the secretion, storage, and synthesizing of renin.
Global Rationale: The juxtaglomerular cells (JG) are responsible for the secretion, storage, and synthesizing of renin. The distal loop and Henle's loop are both sections of the kidneys, not a group of cells. The baroreceptors are located in the heart, not the kidneys.