Author Question: Prior to administering donepezil (Aricept) to a client diagnosed with Alzheimer disease, the nurse ... (Read 105 times)

yoroshambo · **on:** Jul 23, 2018

Prior to administering donepezil (Aricept) to a client diagnosed with Alzheimer disease, the nurse notes that the client is prescribed medications that will react with this drug. Which medications interact with donepezil (Aricept)?

Standard Text: Select all that apply.
1. Phenytoin (Dilantin)
2. Rifampin
3. Quinidine
4. Penicillin
5. Aspirin

Question 2

Prior to administering galantamine (Reminyl) to a client with Alzheimer disease, the nurse reviews the client's medical history for which disease processes?

Standard Text: Select all that apply.
1. Respiratory disorders
2. Liver dysfunction
3. Kidney failure
4. Atrial fibrillation
5. Arthritis

wtf444 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 1,2,3
Rationale 1: Decreased effects of donepezil (Aricept) will occur with concurrent administration of phenytoin (Dilantin).
Rationale 2: Decreased effects of donepezil (Aricept) will occur with concurrent administration of rifampin.
Rationale 3: Metabolism of donepezil (Aricept) may be inhibited by quinidine.
Rationale 4: Donepezil (Aricept) does not interact with penicillin.
Rationale 5: Donepezil (Aricept) does not interact with aspirin.
Global Rationale: Decreased effects of donepezil (Aricept) will occur with concurrent administration of phenytoin (Dilantin), rifampin, and quinidine. Donepezil (Aricept) does not interact with penicillin or aspirin.

Answer to Question 2

Correct Answer: 1,2,3,4
Rationale 1: This medication should be used cautiously in those with respiratory disease.
Rationale 2: This medication is not recommended for use in those with hepatic dysfunction.
Rationale 3: This medication is not recommended for use in those with renal dysfunction.
Rationale 4: This medication is to be used cautiously in those with cardiac conduction disorders.
Rationale 5: This medication is not contraindicated in those with arthritis.
Global Rationale: This medication should be used cautiously in those with respiratory disease, hepatic dysfunction, renal dysfunction, and cardiac conduction disorders. This medication is not contraindicated in those with arthritis.