Answer to Question 1
Correct Answer: 1,2
Rationale 1: Methyldopa (Aldomet) is an alpha2 agonist. It decreases blood pressure; the primary therapeutic application is the treatment of hypertension.
Rationale 2: Clonidine (Catapres) is an alpha2 agonist. It decreases blood pressure; the primary therapeutic application is the treatment of hypertension.
Rationale 3: Tetrahydrozoline (Tyzine) is widely used for minor eye irritation and redness.
Rationale 4: Midodrine (ProAmatine) is converted into an active metabolite that has alpha1-agonist actions. It is given orally for the symptomatic treatment of orthostatic hypotension.
Rationale 5: Pirbuterol (Maxair) is a short-acting beta-adrenergic agonist given by inhalation to terminate acute bronchospasm.
Global Rationale: Methyldopa (Aldomet) and clonidine (Catapres) are alpha2 agonists. They decrease blood pressure; the primary therapeutic application is the treatment of hypertension. Tetrahydrozoline (Tyzine) is widely used for minor eye irritation and redness. Midodrine (ProAmatine) is converted into an active metabolite that has alpha1-agonist actions. It is given orally for the symptomatic treatment of orthostatic hypotension. Pirbuterol (Maxair) is a short-acting beta-adrenergic agonist given by inhalation to terminate acute bronchospasm.
Answer to Question 2
Correct Answer: 1,2
Rationale 1: Drugs used for their beta1-agonist actions are sometimes called cardiotonic drugs because they increase cardiac output.
Rationale 2: Drugs used for their beta1-agonist actions are sometimes called inotropic agents because they increase the strength of myocardial contraction.
Rationale 3: Beta2 agonists relax bronchial smooth muscle.
Rationale 4: Alpha1 agonists are used for hypotension.
Rationale 5: Alpha2 agonists are used for the treatment of hypertension.
Global Rationale: Drugs used for their beta1-agonist actions are sometimes called cardiotonic drugs because they increase cardiac output. These drugs can also be called inotropic agents because they increase the strength of myocardial contraction. Beta2 agonists relax bronchial smooth muscle. Alpha1 agonists are used for hypotension. Alpha2 agonists are used for the treatment of hypertension.