Answer to Question 1
Correct Answer: 2
Rationale 1: Age can be a factor in dosing of medications, but this is not the best explanation of why different doses are needed to for two different people.
Rationale 2: Genetic makeup and metabolism vary widely and account for the differences in response to drugs and the need for individualized doses.
Rationale 3: Taking other medications could be part of the reason why the dose is different, but this is not the best explanation.
Rationale 4: Generic and brand name drugs usually have the same dose equivalency.
Global Rationale: Genetic makeup and metabolism vary widely and account for the differences in response to drugs and the need for individualized doses. Age can be a factor in dosing of medications, but this is not the best explanation of why different doses are needed to for two different people. Taking other medications could be part of the reason why the dose is different, but this is not the best explanation. Generic and brand name drugs usually have the same dose equivalency.
Answer to Question 2
Correct Answer: 2
Rationale 1: A loading dose of a medication is usually only given once. Repeating the loading dose could cause toxicity.
Rationale 2: Following a loading dose, the usual maintenance dose of a drug is given in order to maintain a therapeutic blood level of the drug.
Rationale 3: Alternating high and low doses would not allow for a plateau of the drug level to be reached, which is needed for a therapeutic response.
Rationale 4: Bolus injections are usually only given once, not daily.
Global Rationale: Following a loading dose, the usual maintenance dose of a drug is given in order to maintain a therapeutic blood level of the drug. A loading dose of a medication is usually only given once. Repeating the loading dose could cause toxicity. Alternating high and low doses would not allow for a plateau of the drug level to be reached, which is needed for a therapeutic response. Bolus injections are usually only given once, not daily