Author Question: A nurse is trying to determine whether a patient has experienced an adverse drug reaction. Which ... (Read 38 times)

Capo · **on:** Jul 23, 2018

A nurse is trying to determine whether a patient has experienced an adverse drug reaction. Which question would most likely assist the nurse in this determination?

a. Did the patient notice that the drug caused a bad taste in the mouth?
b. Did the patient's symptoms appear shortly after the drug was first used?
c. Is the patient complaining about the frequency of drug dosing?
d. Has the drug produced this effect in another patient receiving the same agent at the same dose?

Question 2

A nurse is administering morning medications. The nurse gives a patient multiple medications, two of which compete for plasma albumin receptor sites. As a result of this concurrent administration, the nurse can anticipate that what might occur?

(Select all that apply.)
a. Binding of one or both agents is reduced
b. Plasma drug levels of free drug will rise
c. Plasma drug level of free drug will fall
d. The increase in free drug can intensify effects
e. The increase in bound drug can intensify effects

mammy1697 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B
Symptoms that appear shortly after a drug is administered are likely related to the medication and indicative of an adverse reaction.
A bad taste in the mouth is usually considered a side effect of certain medications and is not indicative of an adverse reaction in most cases.
Frequency of drug dosing is not typically associated with adverse drug reactions.
All patients do not react the same to medications, even the same medications.

Answer to Question 2

ANS: A, B, D
When two drugs bind to the same site on plasma albumin, coadministration of those drugs produces competition for binding. As a result, binding of one or both agents is reduced, causing plasma levels of free drug to rise. The increase in free drug can intensify the effect, but usually undergoes rapid elimination. The increase in plasma levels of free drug is rarely sustained.