Answer to Question 1
ANS: B
Ciprofloxacin can elevate levels of warfarin. The prothrombin time should be monitored, and the dosage of warfarin should be reduced as appropriate.
Answer to Question 2
ANS: A
Hepatotoxicity is the greatest concern. Trovafloxacin and alatrofloxacin can cause liver enzyme abnormalities, symptomatic hepatitis, and acute hepatic necrosis.
Weight loss, visual disturbances, and anemia are not associated with trovafloxacin and alatrofloxacin.