A patient is receiving intravenous vancomycin (Vancocin). A ...

[Yolanda]

A patient is receiving intravenous vancomycin (Vancocin). A unique complication of rapid IV infusion of vancomycin is
 
  a. pleural effusion.
  b. angioedema.
  c. red man syndrome.
  d. neurotoxicity.

Question 2

Which statements about the differences between first- and fourth-generation cephalosporins are correct? (Select all that apply.)
 
  a. Fourth-generation agents have more activity against gram-negative organisms.
  b. First-generation agents are more active against anaerobes.
  c. First-generation agents have increased resistance to beta-lactamases.
  d. Fourth-generation agents have an increased ability to reach the cerebrospinal fluid.
  e. First-generation agents are more vulnerable to destruction by beta-lactamases.

[mariahkathleeen]

Answer to Question 1

ANS: C
Rapid infusion of vancomycin can cause flushing, rash, pruritus, urticaria, tachycardia, and hypotension, known collectively as red man syndrome.
Pleural infusion is unlikely with IV vancomycin.
Angioedema is not associated with vancomycin administration.
Neurotoxicity is not associated with rapid infusion of IV vancomycin.

Answer to Question 2

ANS: A, D, E
Fourth-generation agents have more activity against gram-negative organisms and have an increased ability to reach the cerebrospinal fluid. First-generation agents are more vulnerable to destruction by beta-lactamases.
First-generation agents are not more active against anaerobes, nor do they have increased resistance to beta-lactamases.

[Yolanda]

Thanks

[mariahkathleeen]

Welcome