The principal indication for use of nonaspirin NSAIDs is a. ...

[deesands]

The principal indication for use of nonaspirin NSAIDs is
 
  a. fever.
  b. dysmenorrhea.
  c. arthritis.
  d. MI prevention.

Question 2

A mother brings her 17-year-old daughter to the emergency department. She states that the daughter took 40 extended-release acetaminophen tablets 8 hours ago. The nurse would anticipate an order for
 
  a. activated charcoal.
  b. high doses of antacids.
  c. acetylcysteine (Mucomyst).
  d. hemodialysis.

[johnpizzaz]

Answer to Question 1

ANS: C
The principal indication for use of nonaspirin NSAIDs is reduction of the inflammation associated with arthritis.
Nonaspirin NSAIDs may be used to reduce fever, but this is not the principal indication, which is to reduce inflammation.
Nonaspirin NSAIDs may be used for dysmenorrhea, but this is not the principal indication, which is to reduce inflammation.
Nonaspirin NSAIDs do not provide the same benefit that aspirin does for preventing myocardial infarction.

Answer to Question 2

ANS: C
Liver damage can be minimized by giving acetylcysteine (Mucomyst), a specific antidote to acetaminophen. Acetylcysteine reduces injury by substituting for depleted glutathione in the reaction that converts the toxic metabolite of acetaminophen into its nontoxic form when given within 8 to 10 hours.
Because a period of 8 hours has elapsed, it is too late to administer activated charcoal; the medication most likely has already been absorbed.
Antacids, even in high doses, will not correct the problem.
Overdose of acetaminophen is toxic to the liver, not the kidneys, therefore hemodialysis is not indicated.

[deesands]

TYSM

[tkempin]

Thanks for the timely response, appreciate it