Author Question: Which is a characteristic that distinguishes sulfonamides from other drugs used to treat bacterial ... (Read 18 times)

azncindy619 · **on:** Jul 23, 2018

Which is a characteristic that distinguishes sulfonamides from other drugs used to treat bacterial infection?

a. Sulfonamides are bactericidal.
b. Sulfonamides are derived from biologic substances.
c. Sulfonamides have antifungal and antiviral properties.
d. Sulfonamides increase bacterial synthesis of folic acid.

Question 2

The nurse is preparing to administer intravenous gentamicin to an infant through an intermittent needle. The nurse notes that the infant has not had a wet diaper for several hours. The nurse will perform which action?

a. Administer the medication and give the infant extra oral fluids.
b. Contact the provider to request adding intravenous fluids when giving the medication.
c. Give the medication and obtain a serum peak drug level 45 minutes after the dose.
d. Hold the dose and contact the provider to request a serum trough drug level.

raili21 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B
Sulfonamides are bacteriostatic, not bactericidal. They are not derived from biologic substances. They are not antifungals or antivirals. They act by decreasing bacterial synthesis of folic acid.

Answer to Question 2

ANS: D
Gentamicin can cause nephrotoxicity. When changes in urine output occur, the provider should be notified, and serum trough levels should be obtained to make sure the drug is not at a toxic level. If the drug level is determined to be safe, giving extra fluids either orally or intravenously may be indicated. Serum peak levels give information about therapeutic levels but are not a substitution for avoiding nephrotoxicity in the face of possible oliguria.