Author Question: A nursing student asks how nonsteroidal antiinflammatory drugs (NSAIDs) work to suppress ... (Read 80 times)

P68T · **on:** Jul 23, 2018

A nursing student asks how nonsteroidal antiinflammatory drugs (NSAIDs) work to suppress inflammation and reduce pain. The nurse will explain that NSAIDs

a. exert direct actions to cause relaxation of smooth muscle.
b. inhibit cyclooxygenase that is necessary for prostaglandin synthesis.
c. interfere with neuronal pathways associated with prostaglandin action.
d. suppress prostaglandin activity by blocking tissue receptor sites.

Question 2

The nurse is caring for a patient who has multiple sclerosis. The patient is experiencing an acute attack. Which drug does the nurse anticipate the provider will order?

a. Adrenocorticotropic hormone (ACTH)
b. Cyclophosphamide (Cytoxan)
c. Glatiramer acetate (Copaxone)
d. Interferon-B (IFN-B)

lkoler · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B
NSAIDs act by inhibiting COX-1 and COX-2 to help block prostaglandin synthesis. They do not have direct action on tissues, nor do they interfere with chemical receptor sites or neuronal pathways.

Answer to Question 2

ANS: A
ACTH is given to treat an acute attack of MS. Glatiramer acetate and interferon are used for remission-exacerbation states. Cyclophosphamide is given for chronic, progressive symptoms.