Author Question: The majority of drug metabolism is catalyzed by the cytochrome p-450 group of enzymes. When these ... (Read 52 times)

strangeaffliction · **on:** Jul 23, 2018

The majority of drug metabolism is catalyzed by the cytochrome p-450 group of enzymes. When these enzymes are inhibited, a drug simultaneously given will:

A. reach higher-than-intended levels in the body.
B. be inhibited and levels in the body will drop.
C. have no effect in the body.
D. create the potential for anaphylaxis.

Question 2

Phenytoin (Dilantin) is prescribed for a patient with seizures. You know that this drug is gradually increased to achieve a desired level. The patient is taught that maintenance doses for this medication are typically:

1. 50 mg to 75 mg daily.
2. 100 mg to 250 mg daily.
3. 300 mg to 400 mg daily.
4. 450 mg to 500 mg daily.

hugthug12 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

A

Answer to Question 2

3
The usual adult dose of phenytoin (Dilantin) is 100 mg PO 3 times daily initially then gradually increased to achieve desired serum levels. Maintenance doses are usually 300 mg to 400 mg dai-ly.