An Asian patient comes to the clinic. Upon assessment, the nurse ...

[jenna1]

An Asian patient comes to the clinic. Upon assessment, the nurse notes a slight yellow tint to the skin and sclera, edema, and hepatomegaly. The drug history reveals that the patient has been taking rosuvastatin (Crestor) for 6 months.
 
  The nurse is concerned, because rosuvastatin (Crestor) has been shown to a. cause renal and pancreatic toxicity specifically in Asian patients.
  b. cause hepatotoxicity that immediately leads to renal failure.
  c. create myoglobin in the urine, leading to hepatotoxicity.
  d. reach levels twice as high in Asians as in Caucasians, resulting in a greater chance of hepatotoxicity.

Question 2

A patient admitted to the unit for dehydration tells the nurse that he has not had a bowel movement in 5 days, and he typically has one daily. The nurse administers psyllium (Metamucil) as ordered and should monitor the patient for
 
  a. bright red stools.
  b. black, tarry stools.
  c. pale, clay-colored stools.
  d. intestinal obstruction.

[billybob123]

Answer to Question 1

D
Rosuvastatin reaches abnormally high levels in people of Asian heritage. Consequently, hepato-toxicity may occur more often in Asians patients because of the high level of the drug in the blood.
Rosuvastatin does not cause renal and pancreatic toxicity.
Hepatotoxicity does not necessarily lead to renal failure.
Rosuvastatin does not create myoglobin in the urine.

Answer to Question 2

D
Bulk-forming laxatives can cause an intestinal obstruction or impaction if not enough water is consumed. The patient needs concurrent rehydration to prevent this.
Bright red stools would not be anticipated unless the patient has hemorrhoids, and there is no indication of this.
Black, tarry stools typically are seen if blood is present in the stool, no information suggests that the patient has gastrointestinal bleeding.
Pale, clay-colored stools may be apparent if the patient has a hepatic disorder, but no information suggests this.

[jenna1]

Thanks for the timely response, appreciate it

[phuda]

Gracias!