A patient who will begin taking colchicine for gout reports ...

[mckennatimberlake]

A patient who will begin taking colchicine for gout reports taking nonsteroidal anti-inflammatory drugs, simvastatin, amoxicillin, and digoxin. What will the nurse do?
 
  a. Contact the provider to discuss using a different antibiotic while this patient is taking colchicine.
  b. Notify the provider about the potential risk of muscle injury when simvastatin is taken with colchicine.
  c. Request an order for cardiorespiratory monitoring, because the patient is taking digoxin.
  d. Suggest that the nonsteroidal an-ti-inflammatory drugs (NSAIDs) be with-drawn during colchicine therapy.

Question 2

A patient has had three gouty flare-ups in the past year. Which drug class will the nurse expect the provider to order for this patient?
 
  a. Colchicine
  b. Glucocorticoids
  c. Nonsteroidal anti-inflammatory drugs
  d. Urate-lowering drugs

[Moriaki]

Answer to Question 1

B
Colchicine can cause rhabdomyolysis, and this risk is increased in patients who also take sim-vastatin or other statin drugs. Amoxicillin does not interact with colchicine. The side effects of digoxin are not increased by concurrent use with colchicine. NSAIDs can safely be taken with colchicine.

Answer to Question 2

D
The provider will order a urate-lowering drug for this patient. The medication should be diluted and administered with 20 mL of sterile sodium chloride and administered over 5 minutes or longer.

[mckennatimberlake]

TYSM

[xiazhe]

Thanks for the timely response, appreciate it