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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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On average, the stomach produces 2 L of hydrochloric acid per day.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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The toxic levels for lithium carbonate are close to the therapeutic levels. Signs of toxicity include fine hand tremor, polyuria, mild thirst, nausea, general discomfort, diarrhea, vomiting, drowsiness, muscular weakness, lack of coordination, ataxia, giddiness, tinnitus, and blurred vision.