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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Nearly 31 million adults in America have a total cholesterol level that is more than 240 mg per dL.
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The average office desk has 400 times more bacteria on it than a toilet.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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Less than one of every three adults with high LDL cholesterol has the condition under control. Only 48.1% with the condition are being treated for it.