Which medications are most likely to cause postural hypotension? ...

[HCHenry]

Which medications are most likely to cause postural hypotension? (Select all that apply.)
 
  a. Minoxidil
  b. Diltiazem Cardizem
  c. Prazosin Minipress
  d. Captopril Capoten
  e. Losartan Cozaar

Question 2

A nurse is teaching a patient who is about to begin drug therapy with orlistat Xenical. The patient, whose BMI is 28, has hypertension and type 2 diabetes mellitus. Which statement by the patient indicates understanding of the teaching?
 
  a. Dark urine and light-colored stools are expected side effects with this drug.
  b. I should stop taking this drug once my blood pressure and serum glucose have stabilized.
  c. I will need to take a multivitamin con-taining fat-soluble vitamins every day.
  d. If I have fatty or oily stools or fecal in-continence I should stop taking this drug.

[trog]

Answer to Question 1

C, D, E
Postural, or orthostatic, hypotension is defined as a fall in blood pressure related to a change in position. Minoxidil and diltiazem dilate arterioles; therefore, they are not likely to cause postural hypotension. Prazosin, captopril, and losartan all reportedly can cause orthostatic hypotension.

Answer to Question 2

C
Because orlistat works by reducing fat absorption, fat-soluble vitamins are not absorbed as well. Patients should take a multivitamin containing vitamins A, D, E, and K. The increased fat is lost in stools, resulting in fatty, oily stools and fecal incontinence. These are expected side effects but are not dangerous and can be managed with bulk-forming laxatives. Orlistat is used for long-term weight loss and should be given up to 2 years to sustain weight loss. Dark urine and light-colored stools indicate possible liver damage and the need to discontinue the drug until liver damage has been ruled out.

[HCHenry]

Excellent

[Viet Thy]

TYSM