Author Question: A student asks the pharmacy instructor what the difference is between the diuretics spironolactone ... (Read 25 times)

humphriesbr@me.com · **on:** Jul 23, 2018

A student asks the pharmacy instructor what the difference is between the diuretics spironolactone (Aldactone) and furosemide (Lasix). What would the instructor reply?

A) Potassium losses are lower with spironolactone.
B) Potassium losses are greater with spironolactone.
C) Water losses are greater with spironolactone.
D) Sodium losses are greater with spironolactone.

Question 2

The nurse is talking with a group of nursing students. What drug would the nurse tell them, when combined with furosemide (Lasix), is likely to cause hearing loss?

A) Codeine
B) Ciprofloxacin (Cipro)
C) Digoxin (Lanoxin)
D) Gentamicin (Garamycin)

macmac · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

A
Feedback:
Spironolactone is a potassium sparing diuretic; therefore, it promotes retention of potassium. Furosemide promotes greater water, sodium, and potassium losses than spironolactone.

Answer to Question 2

D
Feedback:
The risk of ototoxicity increases if loop diuretics are combined with aminoglycoside antibiotics (gentamicin) or cisplatin. No known increased risk of ototoxicity exists when furosemide is taken with codeine, ciprofloxacin, or digoxin.