Author Question: A patient with type 1 diabetes takes 12 units of regular insulin and 34 units of NPH insulin in the ... (Read 57 times)

hbsimmons88 · **on:** Jul 23, 2018

A patient with type 1 diabetes takes 12 units of regular insulin and 34 units of NPH insulin in the morning. How would the nurse explain why two different types of insulin are required to control the patient's blood sugar?

A) Different onsets and peak effects extends blood glucose control.
B) The mixture makes each drug work more effectively.
C) The combination reduces the adverse effects experienced.
D) Patients are less likely to experience hypoglycemia.

Question 2

The nurse is caring for a patient with renal dysfunction who requires an oral antidiabetic agent. What drug will the nurse expect to see ordered?

A) Tolbutamide
B) Chlorpropamide
C) Tolazamide
D) Chlorpromazine

parshano · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

A
Feedback:
Regular insulin will begin working within 30 to 60 minutes and peak within 2 to 4 hours and a 6- to 12-hour duration of action whereas NPH insulin has an onset of 60 to 90 minutes and peaks in 4 to 12 hours, with a 24-hour duration of action. By giving both drugs at once, the patient gets rapid blood glucose control within 30 minutes from the regular insulin and the control lasts 24 hours due to NPH's long duration of action. The combination does not make the drugs work more effectively, it does not reduce adverse effects, and patients are more likely to experience hypoglycemia if they do not eat properly.

Answer to Question 2

A
Feedback:
Tolbutamide is preferred for patients with renal dysfunction, who may not be able to excrete chlorpropamide, because it is more easily cleared from the body. Tolbutamide, chlorpropamide, and tolazamide are all first-generation sulfonylureas, but tolazamide is used less frequently and is usually tried after the first two drugs have been shown to be ineffective. Chlorpromazine (Thorazine) is an antipsychotic agent.