Author Question: The nurse explains the action of a beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase ... (Read 13 times)

abarnes · **on:** Jul 23, 2018

The nurse explains the action of a beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor as inhibiting what?

A) An enzyme that controls the final step in production of cellular cholesterol
B) An enzyme used immediately for energy
C) An enzyme that combines with proteins to become chylomicrons
D) An enzyme used to make bile acids

Question 2

The nurse is caring for a patient who takes fluvastatin (Lescol). Which laboratory value should be assessed regularly on this patient?

A) Blood urea nitrogen (BUN)
B) Complete blood count (CBC)
C) Activated partial thromboplastin time
D) Liver function studies

fatboyy09 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

A
Feedback:
HMG-CoA reductase is an enzyme that controls the final step in production of cellular cholesterol. Some fats are used immediately for energy. Bile acids act like detergents to break down or metabolize fats into small molecules called micelles, which are absorbed into the intestinal wall and combined with proteins to become chylomicrons, to allow transport throughout the circulatory system. Cholesterol is a fat that is used make bile acids.

Answer to Question 2

D
Feedback:
Increased concentrations of liver enzymes commonly occur, and acute liver failure has been reported with the use of atorvastatin and fluvastatin. Liver function studies should be monitored at the onset of therapy, at 6 and 12 weeks, and intermittently during course of therapy. The other tests would not be pertinent to this specific drug.