The nurse receives an order to administer glycopyrrolate 0.002 ...

[Kikoku]

The nurse receives an order to administer glycopyrrolate 0.002 mg/kg to the pediatric patient preoperatively. The patient weighs 14 lbs. If 1 pound = 2.2 kg, how many kilograms would the nurse administer to this patient?
 
  A) 0.013 mg
  B) 0.13 mg
  C) 0.028 mg
  D) 0.28 mg

Question 2

The nurse often gives another drug with levodopa (L-dopa) to decrease the amount of levodopa needed to reach a therapeutic level in the brain, thereby reducing adverse effects? What is the name of this drug?
 
  A) Bromocriptine
  B) Carbidopa
  C) Amantadine
  D) Trihexyphenidyl

[bigsis44]

Answer to Question 1

A
Feedback:
Begin by calculating the child's weight in kilogram 14 lbs/2.2 kg = 6.36 kg. Multiply child's weight in kg by dosage in kg 6.36  0.002 = 0.01272 rounded to 0.013 mg.

Answer to Question 2

B
Feedback:
Carbidopa is frequently given with levodopa in a fixed-dose combination product called Sinemet or Sinemet CR. When used with carbidopa, the enzyme dopa decarboxylase is inhibited in the periphery, diminishing the metabolism of levodopa in the gastrointestinal (GI) tract and in peripheral tissues, thereby leading to higher levels crossing the bloodbrain barrier. Because carbidopa decreases the amount of levodopa needed to reach a therapeutic level in the brain, the dosage of levodopa can be decreased, which reduces the incidence of adverse effects. Bromocriptine, amantadine, and trihexyphenidyl may be effective longer than levodopa but are not usually prescribed together.

[Kikoku]

Gracias!

[Bigfoot1984]

TYSM