Author Question: The patient is taking ifosfamide as part of his or her cancer treatment. Mesna (Mesnex) is added to ... (Read 8 times)

abarnes · **on:** Jul 23, 2018

The patient is taking ifosfamide as part of his or her cancer treatment. Mesna (Mesnex) is added to the treatment regimen to prevent cystitis induced by the ifosfamide. The nurse explains that mesna works by what action?

A) By increasing urine output
B) By shielding the kidney from ifosfamide
C) By increasing white blood cell production
D) By combining with a metabolite of ifosfamide

Question 2

The nurse is speaking to a group at the senior citizen's center about Parkinson's disease and explains the importance of avoiding what when taking an anticholinergic medication?

A) Strenuous exercise in high environmental temperatures
B) Fluids high in potassium
C) Foods high in vitamin K
D) Anything containing red dye

jennafosdick · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

D
Feedback:
Mesna combines with a urotoxic metabolite of ifosfamide to reduce the damaging effects of ifosfamide. It has no effect on urine output, does not provide a shield for the kidney, and has no impact on white blood cell production.

Answer to Question 2

A
Feedback:
Anticholinergic drugs decrease sweating. As a result, the body is not as effective at reducing internal temperature as this could result in fever and heatstroke. Elderly people taking anticholinergic drugs do not need to avoid fluids high in potassium, foods high in vitamin K, or anything containing red dye.