Author Question: The nurse admits a 1-year-old child to the pediatric intensive care unit (ICU) with cryptococcal ... (Read 74 times)

lunatika · **on:** Jul 23, 2018

The nurse admits a 1-year-old child to the pediatric intensive care unit (ICU) with cryptococcal meningitis. What drug will the nurse anticipate receiving an order for to treat this child?

A) Amphotericin B (Fungizone)
B) Fluconazole (Diflucan)
C) Griseofulvin (Fulvicin)
D) Ketoconazole (Nizoral)

Question 2

A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a Pregnancy Category B drug. What would the nurse inform the patient?

A) Adequate studies in pregnant women have demonstrated there is no risk to the fetus.
B) Animal studies have not demonstrated a risk to the fetus, but there have been no adequate studies in pregnant women.
C) Animal studies have shown an adverse effect on the fetus, but there are no adequate studies in pregnant women.
D) There is evidence of human fetal risk, but the potential benefits from use of the drug may be acceptable despite potential risks.

miss_1456@hotmail.com · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

B
Feedback:
Fluconazole is used in the treatment of cryptococcal meningitis and is safe to use in a 1-year-old child. Amphotericin B has many unpleasant adverse effects and is very potent, so it would not be the first or best medication to administer initially but would be reserved for use if fluconazole was not effective. Griseofulvin is given to treat tinea pedis and tinea unguium in children. Ketoconazole is not given to children younger than 2 years because safety has not been established.

Answer to Question 2

B
Feedback:
Category B indicates that animal studies have not demonstrated a risk to the fetus. However, there have not been adequate studies in pregnant women to demonstrate risk to a fetus during the first trimester of pregnancy and no evidence of risk in later trimesters. Category A indicates that adequate studies in pregnant women have not demonstrated a risk to the fetus in the first trimester or in later trimesters. Category C indicates that animal studies have shown an adverse effect on the fetus, but no adequate studies in humans. Category D reveals evidence of human fetal risk, but the potential benefits from the use of the drugs in pregnant women may outweigh potential risks.