A patient is taking cimetidine (Tagamet) for increased gastric ...

[rlane42]

A patient is taking cimetidine (Tagamet) for increased gastric pain and hypersecretion. Nurses should use extreme caution when administering cimetidine to patients with which of the following conditions?
 
  A) Hepatic disease
  B) Cancer
  C) Hypertension
  D) Diabetes mellitus

Question 2

The nurse practitioner instructs the patient to use over-the-counter ranitidine (Zantac) instead of cimetidine (Tagamet). What risk is decreased when using ranitidine rather than cimetidine?
 
  A) Headache
  B) Drug-to-drug interaction
  C) Diarrhea
  D) Bradycardia

[ecabral0]

Answer to Question 1

A
Feedback:
No absolute contraindications exist, but cimetidine should be used cautiously in patients with impaired hepatic and renal function. The patient with cancer, hypertension, and diabetes mellitus can take cimetidine safely.

Answer to Question 2

B
Feedback:
Unlike cimetidine, ranitidine (Zantac), famotidine (Pepcid, Pepcid RPD), and nizatidine (Axid) do not affect the cytochrome P450 drug-metabolizing system in the liver and therefore do not interfere with the metabolism of other drugs. Use of these other drugs may be preferable in patients who are critically ill because they often require numerous other drugs with which cimetidine may interact.

[rlane42]

Excellent

[chereeb]

Gracias!