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Colchicine is a highly poisonous alkaloid originally extracted from a type of saffron plant that is used mainly to treat gout.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Cyanide works by making the human body unable to use oxygen.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Pregnant women usually experience a heightened sense of smell beginning late in the first trimester. Some experts call this the body's way of protecting a pregnant woman from foods that are unsafe for the fetus.

