A patient is administered rifampin (Rifadin). Which of the ...

[FButt]

A patient is administered rifampin (Rifadin). Which of the following facts should the patient be taught?
 
  A) When taking it with warfarin (Coumadin), an increased anticoagulant effect occurs.
  B) It decreases hepatic enzymes and decreases metabolism of drugs.
  C) It has an increased serum half-life, so it is more effective than rifabutin (Mycobutin).
  D) The urine, tears, sweat, and other body fluids will be a discolored red-orange.

Question 2

When acetylsalicylic acid (aspirin) is administered in low doses, it blocks the synthesis of thromboxane A2 . What physiological effect results from this action?
 
  A) Inflammation is relieved.
  B) Core body temperature is reduced.
  C) Pain is relieved.
  D) Platelet aggregation is inhibited.

[mcarey591]

Answer to Question 1

D
Feedback:
The patient's urine, tears, sweat, and other body fluids will be a discolored red-orange. This adverse effect is harmless, but the patient should be instructed on this adverse effect. The administration of this medication with warfarin will decrease the anticoagulant effect. The medication increases hepatic cytochrome P450 3A4 enzyme and decreases serum concentrations. The serum half-life of rifampin is shorter than that of the medication rifabutin.

Answer to Question 2

D
Feedback:
At low doses, aspirin blocks the synthesis of thromboxane A2 to inhibit platelet aggregation; this lasts for the life of the platelet.

[FButt]

Both answers were spot on, thank you once again

[mcarey591]

Great! Please up vote