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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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There are more sensory neurons in the tongue than in any other part of the body.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.