Author Question: A patient is admitted with glomerulonephritis. IV gentamicin therapy is started after cultures ... (Read 11 times)

ARLKQ · **on:** Jul 24, 2018

A patient is admitted with glomerulonephritis. IV gentamicin therapy is started after cultures indicate gram-negative bacilli in the blood. The patient also receives IV furosemide (Lasix).

The nurse will monitor for signs and symptoms of toxicity related to which organ?
a. Kidneys
b. Pancreas
c. Liver
d. Brain

Question 2

A patient is scheduled to take tetracycline and aluminum hydroxide (Amphojel) at the same time. When will the nurse administer the medications to achieve the optimal effects?

a. Both medications together
b. Amphojel 30 minutes before tetracycline
c. Tetracycline with orange juice
d. Tetracycline 1 hour before Amphojel

CourtneyCNorton · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: A
The results of urinalysis and kidney function tests should be closely monitored when a patient is on aminoglycoside therapy. Patients also receiving cephalosporins, enflurane, methoxyflurane, vancomycin, and diuretics, when combined with aminoglycosides, have a greater potential for nephrotoxicity. The pancreas is not vulnerable to damage from aminogylcosides. Bone marrow suppression is a result of toxicity from treatment with chloramphenicol. Central nervous system toxicities may result from toxic effects of treatment with aminoglycosides but are not related to interactions between the antibiotic and diuretics.

Answer to Question 2

ANS: D
For optimal effectiveness, tetracyclines should be administered 1 hour before or 2 hours after ingesting antacids, milk, or other dairy products or products containing calcium, aluminum, magnesium, or iron. Taking the drugs this closely together will most likely inhibit absorption of the antibiotic. Tetracycline does not tend to interact with orange juice, but the beverage may be contraindicated in a patient who needs to take antacids.