Author Question: A patient is beginning the second round of high-dose cisplatin. Severe, chemotherapy-induced nausea ... (Read 44 times)

Mr3Hunna · **on:** Jul 24, 2018

A patient is beginning the second round of high-dose cisplatin. Severe, chemotherapy-induced nausea and vomiting (CINV) occurred following the first treatment, requiring 72 hours of continuous IV hydration.

In addition to her chemotherapy regimen, which medication would be best to administer?
a. Prochlorperazine (Compazine) suppository daily, on the day of treatment and the next 3 days
b. Anticholinergic agents, such as diphenhydramine or meclizine
c. Parenteral ondansetron 1 hour before chemotherapy, with oral ondansetron to continue for the next 4 days
d. Parenteral ondansetron during chemotherapy, with prochlorperazine suppositories daily for 1 week

Question 2

The nurse is discussing dietary and lifestyle changes with a patient diagnosed with GERD. When reviewing necessary modifications, the nurse will include information regarding (Select all that apply.)

a. limiting coffee intake to 2 cups/day.
b. smoking cessation.
c. avoiding NSAIDs.
d. decreasing protein foods.
e. using nonfat milk.

laurnthompson · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: C
With the patient's first treatment history and the emetogenic chemotherapy agent, cisplatin, ondansetron has shown to be the most effective for prevention of severe nausea and vomiting. Prochlorperazine and anticholinergic agents are not used for the treatment of CINV. The ondansetron should be administered 1 hour before the chemotherapy and continued for the next several days to prevent vomiting and dehydration associated with chemotherapy administration.

Answer to Question 2

ANS: B, C, E
Interventions to help relieve symptoms associated with GERD include cessation of smoking, avoidance of NSAIDs, and use of nonfat milk. Coffee should be avoided completely. Protein foods should be increased.