What is the action of zafirlukast (Accolate), a leukotriene ...

[lak]

What is the action of zafirlukast (Accolate), a leukotriene receptor antagonist?
 
  a. Dilates the alveolar sacs
  b. Decreases leukotriene release
  c. Inhibits histamine release
  d. Increases viscosity of secretions

Question 2

Premedication assessments before the use of anticholinergic bronchodilating agents should verify that the patient has no history of which condition?
 
  a. Diabetes
  b. Hypertension
  c. Liver disease
  d. Glaucoma

[CourtneyCNorton]

Answer to Question 1

ANS: B
Leukotrienes are a class of anti-inflammatory agents that block leukotriene formation, and they are part of the inflammatory pathway that causes bronchoconstriction . Leukotrienes work to reduce bronchoconstriction, and they do not inhibit histamine release or affect viscosity of secretions.

Answer to Question 2

ANS: D
Anticholinergic bronchodilating agents cause mydriasis (dilation of the pupils) and cycloplegia (loss of power in the ciliary muscle); therefore, they should not be used in patients with a history of closed-angle glaucoma. Diabetes, hypertension, and liver disease are not affected by the use of anticholinergic bronchodilating agents.

[lak]

Gracias!

[Joy Chen]

Thanks for the timely response, appreciate it