Author Question: Which intervention would be considered to reduce accumulation of a drug in a patient who has ... (Read 38 times)

acc299 · **on:** Jul 24, 2018

Which intervention would be considered to reduce accumulation of a drug in a patient who has decreased liver function?

a. Decreasing the time interval between dosages
b. Reducing the dosage
c. Administering the medication intravenously
d. Changing the drug to one that has a longer half-life

Question 2

Which classification of medications commonly causes allergic reactions in children?

a. Antacids
b. Analgesics
c. Antibiotics
d. Anticonvulsants

blakeserpa · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: B
Dosages must be reduced to prevent accumulation. Decreasing the time interval between dosages would increase the accumulation of the drug. The intravenous route has the fastest absorption and with liver dysfunction would increase the accumulation of the drug. A similar drug with a longer half-life would stay in the system longer; with impaired liver function, the result would be increased accumulation.

Answer to Question 2

ANS: C
Antibiotics, especially penicillins, commonly cause allergic reactions in children. Intravenous antibiotics can cause rapid reactions; therefore, the pediatric patient's response to a medication should be assessed and monitored closely. Antacids rarely cause allergic reactions. Children are not particularly allergic to analgesics or anticonvulsants.