Author Question: Which medication is not an ester? 1. Chloroprocaine (Nesacaine) 2. Bupivicaine (Marcaine) 3. ... (Read 29 times)

kfurse · **on:** Jul 24, 2018

Which medication is not an ester?

1. Chloroprocaine (Nesacaine)
2. Bupivicaine (Marcaine)
3. Benzocaine (Americaine)
4. Tetracaine (Pontocaine)

Question 2

A nurse educator is instructing students about the history of anesthetics. Which type of anesthetic would the educator tell the students was the ester of choice from the mid-1900s to the 1960s?

1. Cocaine
2. Benzocaine (Solarcaine)
3. Procaine (Novocain)
4. Lidocaine (Xylocaine)

robbielu01 · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

Correct Answer: 2

Rationale 1: Chloroprocaine (Nesacaine) is an ester.
Rationale 2: Bupivicaine (Marcaine) is an amide.
Rationale 3: Benzocaine (Americaine) is an ester.
Rationale 4: Tetracaine (Pontocaine) is an ester.

Global Rationale: Bupivicaine (Marcaine) is an amide. Chloroprocaine (Nesacaine) is an ester. Benzocaine (Americaine) is an ester. Tetracaine (Pontocaine) is an ester.

Answer to Question 2

Correct Answer: 3

Rationale 1: Cocaine is a natural ester, found in the leaves of the plant Erythroxylon coca, and used for eye surgery, nerve blocks, and spinal anesthesia.
Rationale 2: Benzocaine (Solarcaine and others) is used as a topical OTC agent for treating a large number of painful conditions, including sunburn, insect bites, hemorrhoids, sore throat, and minor wounds.
Rationale 3: Procaine (Novocain) was the drug of choice for dental procedures from the mid-1900s to the 1960s. About that time, amide anesthetics were developed, and use of the ester anesthetics declined.
Rationale 4: Lidocaine (Xylocaine) is the most widely used amide for short surgical procedures requiring local anesthesia.

Global Rationale: Procaine (Novocain) was the drug of choice for dental procedures from the mid-1900s to the 1960s. About that time, amide anesthetics were developed, and use of the ester anesthetics declined. Cocaine is a natural ester, found in the leaves of the plant Erythroxylon coca, and used for eye surgery, nerve blocks, and spinal anesthesia. Benzocaine (Solarcaine and others) is used as a topical OTC agent for treating a large number of painful conditions, including sunburn, insect bites, hemorrhoids, sore throat, and minor wounds. Lidocaine (Xylocaine) is the most widely used amide for short surgical procedures requiring local anesthesia.