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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).
Persons who overdose with cardiac glycosides have a better chance of overall survival if they can survive the first 24 hours after the overdose.
About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.