After administering cyclophosphamide to a client the nurse ...

[kaid0807]

After administering cyclophosphamide to a client the nurse should:
 
  a. continue to monitor the client's urine pH.
  b. administer leucovorin to decrease serum uric acid.
  c. administer mesna to rescue the bladder.
  d. add sodium bicarbonate to the IV fluids.

Question 2

When caring for a client receiving a methotrexate infusion, the nurse should:
 
  a. administer leucovorin immediately after the infusion of methotrexate.
  b. increase the client's intravenous fluids, if the specific gravity falls below 1.010.
  c. discontinue the infusion, if nausea and vomiting develop.
  d. premedicate the client with prednisone to prevent hemorrhagic cystitis.

[Tonny]

Answer to Question 1

ANS: C

Feedback
A Incorrect: The nurse should continue to monitor urine specific gravity.
B Incorrect: This is appropriate for methotrexate administration.
C Correct: Cyclophosphamide can cause hemorrhagic cystitis, so mesna is administered immediately after cyclophosphamide administration and at prescribed intervals for 24 hours.
D Incorrect: The is associated with methotrexate.

Answer to Question 2

ANS: A

Feedback
A Correct: This is the appropriate nursing action. Leucovorin competes with methotrexate at the cellular level to decrease uric acid levels.
B Incorrect: This is not specific to methotrexate.
C Incorrect: The med should not be discontinued but rather an antiemetic may be prescribed.
D Incorrect: Methotrexate is not associated with hemorrhagic cystitis.

[kaid0807]

Thanks for the timely response, appreciate it

[scottmt]

TYSM