Author Question: The nurse closely monitors intravenous administration of colchicines because: a. extravasation ... (Read 33 times)

codyclark · **on:** Jul 24, 2018

The nurse closely monitors intravenous administration of colchicines because:

a. extravasation may lead to tissue necrosis.
b. there is a narrow margin between safe and toxic doses.
c. gastrointestinal side effects are increased with intravenous administration.
d. it is contraindicated in clients with a sulfa allergy.

Question 2

The nurse is caring for a client receiving 6-mercaptopurine (Purinethol) as part of her chemotherapy regimen. This client should avoid:

a. allopurinol. c. probenecid.
c colchicine. d. sulfinpyrazone.

jointhecircus · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: A

Feedback
A Correct: Extravasation from small venous sites may lead to pain and tissue necrosis.
B Incorrect: This is a false statement.
C Incorrect: This is a false statement as GI symptoms are worse with oral administration.
D Incorrect: This is a false statement.

Answer to Question 2

ANS: A

Feedback
A Correct: Allopurinol should be avoided with 6-mercaptopurine, azathioprine, and anticoagulants.
B Incorrect: Colchicine does not need to be avoided with 6-mercaptopurine.
C Incorrect: Probenecid does not need to be avoided with 6-mercaptopurine.
D Incorrect: Sulfinpyrazone does not need to be avoided with 6-mercaptopurine.