A client receiving adalimumab asks the nurse how this drug works ...

[KWilfred]

A client receiving adalimumab asks the nurse how this drug works to treat her RA. The nurse's response is based on knowledge that biologic response modifiers, the newest of the DMARDs:
 
  a. bind with tumor necrosis factor to block normal inflammatory and immune responses.
  b. increase the level of TNF to prevent inflammation without altering the body's immune responses.
  c. block prostaglandins in the joints to decrease inflammation and pain.
  d. inhibit antibody production as well as the release of enzymes from phagocytizing leukocytes.

Question 2

Clients receiving long-term corticosteroid therapy may require dietary modifications. All of the following statements are true about special diets for long-term corticosteroid therapy except:
 
  a. A sodium restricted diet may be needed due to sodium and water retention.
  b. A high-protein, high-carbohydrate diet may be needed to correct negative nitrogen balance.
  c. A potassium-restricted diet may be needed due to potassium retention.
  d. Increased calcium is encouraged to help prevent osteoporosis.

[meryzewe]

Answer to Question 1

ANS: A

Feedback
A Correct: This is the action of biologic response modifiers.
B Incorrect: Biologic response modifiers inactivate TNF.
C Incorrect: This is the action of NSAIDs.
D Incorrect: This is the presumed action of gold compounds.

Answer to Question 2

ANS: C

Feedback
A Incorrect: This is a true statement and should be included in dietary teaching.
B Incorrect: This is a true statement and should be included in dietary teaching.
C Correct: Potassium depletion is a problem with corticosteroid therapy, so diet would not be potassium restricted.
D Incorrect: This is a true statement and should be included in dietary teaching.