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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
Many supplement containers do not even contain what their labels say. There are many documented reports of products containing much less, or more, that what is listed on their labels. They may also contain undisclosed prescription drugs and even contaminants.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.