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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.