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Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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The horizontal fraction bar was introduced by the Arabs.