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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.
Over time, chronic hepatitis B virus and hepatitis C virus infections can progress to advanced liver disease, liver failure, and hepatocellular carcinoma. Unlike other forms, more than 80% of hepatitis C infections become chronic and lead to liver disease. When combined with hepatitis B, hepatitis C now accounts for 75% percent of all cases of liver disease around the world. Liver failure caused by hepatitis C is now leading cause of liver transplants in the United States.
This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.