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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.