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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.