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Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
In 1864, the first barbiturate (barbituric acid) was synthesized.
The oldest recorded age was 122. Madame Jeanne Calment was born in France in 1875 and died in 1997. She was a vegetarian and loved olive oil, port wine, and chocolate.