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Liver spots have nothing whatsoever to do with the liver. They are a type of freckles commonly seen in older adults who have been out in the sun without sufficient sunscreen.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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In 1864, the first barbiturate (barbituric acid) was synthesized.