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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Patients who have been on total parenteral nutrition for more than a few days may need to have foods gradually reintroduced to give the digestive tract time to start working again.
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Asthma cases in Americans are about 75% higher today than they were in 1980.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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There are approximately 3 million unintended pregnancies in the United States each year.