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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The average human gut is home to perhaps 500 to 1,000 different species of bacteria.
As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
There are more bacteria in your mouth than there are people in the world.